Samuel Estragon was a Human archaeologist who devoted half his life to finding the Tox Uthat and was questioned by the Department of Temporal Investigations several times.

In 2366, Estragon died and his assistant, Vash, stole his notes and used them to discover the Tox Uthat on Risa. (TNG episode: "Captain's Holiday", DTI novel: Watching the Clock)

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