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Sphinx may refer to:
- Mythology and religion:
- Sphinx, a figure from Greek mythology
- Starships and vehicles
- USS Sphinx (Centaurus-class), a Federation Centaurus-class personnel transport active in the mid-23rd century
- Sphinx workpod, a type of industrial manipulator used by the Federation in the 24th century
- USS Sphinx (NCC-93469), a Federation Chimera-class heavy destroyer active in the early 25th century