Starfleet Cultural Affairs is a division of Starfleet. Admiral Upton worked in Cultural Affairs in 2379 when he ordered Captain Jean-Luc Picard and the USS Enterprise-E to deal with a developing civil war on Delta Sigma IV. (TNG novels: A Time to Love, A Time to Hate)

Cultural Affairs was sometimes considered not to be of much importance (at least by then presidential candidate Nanietta Bacco. (TNG novel: A Time for War, A Time for Peace)

Divisions and agencies of Starfleet
	Academy • Administration • Advanced Starship Design Bureau • Advanced Technologies • Appeals Board • Bureau of Information • Bureau of Standards • Command • Communications • Control • Corps of Engineers • Criminal Investigative Service • Cultural Affairs • Dental • Exploratory Division • Headquarters • Intelligence • Inspector General • Internal Affairs • Judge Advocate General • Marine Corps • Materiel Supply Command • Medical • Mission Operations • Operations • OSHC • Orbital Operations • Research and Development • Sector Guard • Security • Special Security Division • Science • Shipyards Operations • Stellar Imaging • Strategic Command • Tactical • Technology Assessment Directorate • Training Command