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Details and historyEdit
In the year 2373, Starfleet Science concluded that polaron radiation would destabilize the physiology of a Changeling and reveal any impersonating a humanoid as the Changeling would be unable to hold the assumed form. (DS9 episode: "Apocalypse Rising")
In 2374, Starfleet science assigned Jean-Luc Picard and the crew of the starship USS Enterprise to assist Lem Faal in an attempt to create an artificial wormhole. (TNG - The Q Continuum novels: Q-Space, Q-Zone, Q-Strike)