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This is a list of Federation starships that have been lost or destroyed.

Name Registry Reason Source
USS Ahwahnee NCC-73620 Destroyed at the Battle of Wolf 359 in 2367 The Best of Both Worlds
USS Alexey Leonov Destroyed over Korvat during the Borg Invasion of 2381. ST - Destiny novel: Gods of Night
USS Antares NCC-501 Destroyed by Charles Evans in 2266 Charlie X
USS Archon NCC-189 Destroyed at Beta III in 2167 The Return of the Archons
USS Billings Destroyed when it rammed a Borg Cube over Vulcan in 2381. ST - Destiny novel: Lost Souls
USS Buran NCC-57580 Destroyed at the Battle of Wolf 359 in 2367 The Best of Both Worlds
USS Cairo NCC-42136 Lost, presumed destroyed by the Jem'Hadar, in 2374 In the Pale Moonlight
USS Constellation NCC-1017 Destroyed in 2267 by a planet killer The Doomsday Machine
USS Defiant NX-74205 Destroyed by the Breen in 2375 The Changing Face of Evil
USS Enterprise NCC-1701 Destroyed by Admiral James T. Kirk in 2285 Star Trek III: The Search for Spock
USS Enterprise NCC-1701-C Destroyed by Romulans in 2344 Yesterday's Enterprise
USS Enterprise NCC-1701-D Destroyed by Klingons in 2371 Star Trek Generations
USS Essex NCC-173 Destroyed in 2167 by an electro-magnetic storm in the atmosphere of a Class M moon of planet Mab-Bu VI Power Play
USS Excalibur NCC-1664 Destroyed by the USS Enterprise while under control of the M-5 multi-tronic computer in a war game in 2268 The Ultimate Computer
USS Gage NCC-11672 Destroyed at the Battle of Wolf 359 in 2367 Emissary
USS Gander Destroyed by Jem'Hadar in 2375 Penumbra
USS Ganges NCC-72454 Destroyed by a T'lani vessel in 2370 Armageddon Game
USS Gibraltar Destroyed by a Borg Cube over Korvat during Borg Invasion of 2381 ST - Destiny novel: Gods of Night
USS Grissom NCC-42857 Destroyed by the Dominion in 2375 Field of Fire
USS Horatio NCC-10532 Destroyed in 2364 at Dytallix B, believed to have been caused by sabotage Conspiracy
USS Horizon NCC-176 Destroyed at Sigma Iotia II in 2168 A Piece of the Action
USS Intrepid NCC-1631 Destroyed by a space-faring amoeba near the Gamma 7A System in 2268 The Immunity Syndrome
USS Kelly lost at the Battle of Rigel Trill: Unjoined
USS Malinche NCC-38997 Destroyed in 2381 fighting Borg cubes en route to Andoria ST novel: A Singular Destiny
USS Mekong NCC-72617 Destroyed in 2371 during the failed Cardassian and Romulan assault on the Founders' Homeworld in the Omarian Nebula The Die is Cast
USS Melbourne NCC-62043 Destroyed at the Battle of Wolf 359 in 2367 Emissary
USS Musashi Destroyed in 2381 over Deneva during the Borg Invasion of 2381 when it detonate all of its transphasic torpedoes. ST - Destiny novel: Lost Souls
USS Odyssey NCC-71832 Destroyed by Jem'Hadar in 2370 The Jem'Hadar
USS Orinoco NCC-72905 Destroyed in 2372 by the Cardassian separatist group "The True Way" Our Man Bashir
USS Pasteur NCC-58925 Destroyed by a warp core breach in an alternate future in 2395 following a Klingon attack All Good Things...
USS Roosevelt NCC-2573 Destroyed by the Borg at the Battle of Wolf 359 in 2367 Unity
USS Tirpitz Destroyed by Borg cube over Deneva during Borg Invasion of 2381. ST - Destiny novel: Lost Souls
USS Valiant NCC-74210 Destroyed by the Dominion in 2374 Valiant
USS Yamaguchi NCC-26510 Destroyed at the Battle of Wolf 359 in 2367 The Best of Both Worlds
USS Yamato NCC-71807 Destroyed by Iconian computer virus in 2365 Contagion
USS Yangtzee Kiang NCC-72453 Crashed on a penal moon in the Gamma Quadrant in 2369, having been fired upon in orbit Battle Lines
USS Yukon NCC-74602 Destroyed by the USS Defiant in 2373 during an attempt by a Changeling infiltrator to use the runabout to blow up the Bajoran sun By Inferno's Light

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