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Synthotonin was a component of Federation bio-neural gel packs, which reduced the cell activity levels of the circuits for periodic cellular regeneration. In a normal maintenance cycle, synthononin would be introduced into a gel pack once a month, with only one unit being affected at any one time. In the early 2370s, the USS Voyager suffered shipwide power failures when all gel packs were infused with synthotonin simultaneously. (VOY short story: "Good Night, Voyager")