T'Les was a faculty member of the Vulcan Science Academy, and an outspoken proponent of the pacifistic teachings of Surak. Several years prior to 2155, T'Les resigned her position, and disappeared from public life. She was rumored to have joined the rebellion against the Terran Empire on planet Vulcan.
T'Les was reportedly killed when the Empire attacked the rebel cell at the T'Karath Sanctuary. However, it was not generally known that T'Pau, a rebel leader on Vulcan, had ordered Staal to have her killed. (ENT - Mirror Universe novel: Age of the Empress)