The Talos star group was a multiple star system. (TOS episode: "The Cage"; TOS episode & Star Trek 4 novelization: The Menagerie)
This star group consists of mainly white dwarf stars and 'stellar corpses', which have no life of any kind.
One red giant still supports a system of eleven planets, five terrestrial and six gas giants. The fourth, Talos IV, has a dying race of telepathic humanoids. (ST reference: The Worlds of the Federation)
Talos was the ostensible origin point of James T. Kirk's expedition aboard the yacht starship Plush Princess prior to arrival in the Beta Promethean system in 2293. Spock revealed this falsehood about the yacht's travel path when contacted by the Beta Promethean's traffic control. (TOS novel: The Fearful Summons)
In an alternate timeline, TNC-98422 was the Interstellar Coalition's designation for the Talos star group. (Star Trek: Myriad Universes novel: A Less Perfect Union)
- Since the regular timeline's Federation also uses the TNC as a catalog system to number stellar discoveries, it's possible this name is an alternate name in the regular timeline as well.