The Tholian Ambassador to the United Federation of Planets is the individual in the government of the Tholian Assembly responsible for representing the Tholian government and its policies to the Federation, and vice versa. The Tholian Ambassador to the United Federation of Planets heads up the Tholian diplomatic mission to the UFP, and helps coordinate Tholian foreign policy towards the Federation. The Tholian Ambassador typically resides in the Tholian Embassy on Earth.

In 2381, the Tholian Ambassador to the UFP was Tezrene. (ST - Destiny novel: Mere Mortals)