They are notable for being voracious eaters, as well as for their rapid rate of procreation. Observed to "neither toil or spin", they are known for their affectionate nature and the calming nature of their purring. These characteristics, however, are replaced with animosity when in the presence of Klingons. (TOSepisode: "The Trouble With Tribbles")
A tribble population was nearly accidentally unleashed on the 21st century Earth by Voula, a time-traveling 27th century Starfleet officer, whose timeship had a tribble infestation aboard. Voula wanted to destroy the creatures with her phaser, but Commander Sean Christopher stopped her, and, with the help of cadets at the newly-formed Starfleet Academy, safely gathered them into a storage container. (ST performance: Star Trek Live)
The Klingons tried many methods to rid themselves of the tribbles, none fully successful. Hundreds were packed into life pods and ejected from the ship. One such pod went through a micro-wormhole and ended up in the Delta Quadrant, where it was discovered by a Borg cube which assimilated the surviving tribbles. (TOSshort story: "The Trouble with Borg Tribbles")
A giant tribble, one of Cyrano Jones' "safe" tribbles.
The Enterprise encountered Cyrano Jones, the man who had sold them the tribbles, aboard K-7, while escorting some grain to Sherman's Planet. Jones had a stock of genetically engineered "Safe" tribbles. However, these tribbles grew to immense sizes as they consumed food. When hit with phaser blasts, the giant tribbles could break into thousands of normal-sized tribbles. With minor treatment they could be indeed made 'safe' tribbles. (TASepisode: "More Tribbles, More Troubles")
In reference stardate 2/1412, a seedy Orion man in the Shadow Market of Daros IV had tribbles he claimed were genetically altered to not reproduce. He asked for 100 credits but could be haggled down to 25. As guaranteed, the tribble was sterile, but died within 24 hours. It was in fact a stuffed fake, equipped with a cheap battery-powered device that made it purr on touch. (FASA RPGmodule: Orion Ruse)
A population of tribbles was introduced to Deep Space 9 after the USS Defiant returned from an accidental time-traveling trip back to the 23rd century, in which they visited Deep Space Station K-7, as well as the USS Enterprise of the time. When the Defiant returned to the present, some tribbles had apparently stowed away and were then introduced to Deep Space 9. The DS9 crew had difficulty removing the tribbles. (DS9episode: "Trials and Tribble-ations")
During the clean-up effort on DS9, the senior staff sat around a table at Quark's and discussed their various theories and supposed experiences regarding the origin of tribbles, how the Klingons got their head ridges, and why the Klingons and tribbles hate each other so much. Their speculations included the tribbles being the cause of the ridged-forehead Klingons, among others. (DS9comic: "Nobody Knows the Tribbles I've Seen")
By 2409, some tribbles had been assimilated into the Borg Collective. However, these tiny drones weren't a threat to members of Starfleet. Therefore, many Starfleet officers continued to use assimilated tribbles as pets. As they were linked into the Borg Collective, they could provide their owners with insight into the actions of the Borg.
The assimilated tribbles, called Tribble of Borg, can be purchased in the game's C-store.
Exposure to a wide variety of environments and diets meant that by the twenty-fifth century, more than two dozen sub-species of tribble were known to exist, including some that demonstrated no fear of Klingons in their vicinity. (STOvideo game: Star Trek Online)
In 2409, the Federation was attempting to recreate the original tribble homeworld's ecosystem on one of the moons of Minas Korva. (STOmission: "The Tribble with Klingons")
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