Tuscany (or Toscana) is a region on Earth, in the nation-state of Italy. The Tuscany region is located in northwestern Italy. The capital city of this region is Florence.
In 2355, Elias Vaughn, Ruriko Tenmei and Prynn Tenmei lived in Tuscany. (DS9 - Mission Gamma novel: Lesser Evil, DS9 - Worlds of Star Trek: Deep Space Nine novel: Andor: Paradigm)
Kathryn Janeway promised herself that when the mutations plaguing the crew of the USS Voyager had run their course that she would spend a few days in a holodeck recreation of renaissance-era Tuscany. Lieutenant Commander Tuvok promised to join her for a glass of wine. (VOY episode: "Scientific Method")