The Twelfthray are a powerful civilization who were known to have visited the galaxys Gamma Quadrant.

In the year 2376, Neane Tee mentioned the Twelfthray, along with the Metrons, Organians, BiaMertis and the Q, as possibly being responsible for interspatial gateways that the Even Odds crew had heard were opening all over the Gamma Quadrant. (DS9 novel: Rising Son)

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