- For other uses, see Jefferson.
In 2284, Commander Matthew Renolds assumed command of the Jefferson after his previous command, the Miranda-class USS Polaris, was critically damaged while defending Sherman's Planet from a Klingon attack. Transferring with him was the bulk of the Polaris's command crew.
Shortly after, the Jefferson was instrumental in defeating Captain John Daine, who had betrayed information to the Romulans regarding the location of peace talks between the Federation and Klingons. John Daine's starship, the enormous dreadnought USS Martel, had tried to flee into Romulan space. After Renolds was unable to convince his former friend to come back to Earth, the Martel engaged the Jefferson.
The Martel's impressive weaponry held back the Jefferson until three Klingon Birds-of-Prey arrived to kill Daine for his betrayal. They drew his fire long enough for the Jefferson to penetrate the Martel's defenses and destroy the ship.