The USS Mary Rose was a Starfleet starship in service during the late 2280s.

In 2286, the Mary Rose was part of a fleet tasked with opposing a Klingon fleet attempting to invade the Federation under false flag of truce. The captain of the Mary Rose was convinced by Klingon fleet commander Morith's claims of a peaceful race of New Klingons, and lowered the ship's shields in response. Captain James T. Kirk then sent Mary Rose's captain a message requesting she raise shields again, and referencing General Order 30. (TOS novel: Timetrap)