The USS Nansen was a starship in service to Starfleet in the late 24th century. As of early 2381, it was under the command of Captain Martina Cukovich.

That year, in the aftermath of the recent Borg Invasion, Cukovich and the Nansen were ordered by Admiral Leonard James Akaar to Pacifica, in order to relieve Jean-Luc Picard of command of the USS Enterprise-E, already in orbit. Once accomplished, Cukovich volunteered the Nansen and its crew to continue the work already started in alleviating the problems at Pacifica's iy'Dewra'ni refugee camp. The Nansen then took aboard a number of stranded Kazarites, Cygneti, Dopterians, Pentamians, and others, to return them to their home worlds. (TNG novel: Losing the Peace)

The Nansen is likely named after Fridtjof Nansen, a League of Nations High Commissioner for the refugees of World War I.

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