USS Nebula may refer to:

• Prime reality:
  • USS Nebula (NCC-2502), a Constellation-class starship.
  • USS Nebula (NCC-60202), a Nebula-class starship.
• Alternate reality
  • USS Nebula, an Arbiter-class missile cruiser.
  • USS Nebula, a Constitution-class flagship.
  • USS Nebula, a Defender-class bomber.
  • USS Nebula, a Guardian-class support frigate.
  • USS Nebula, an Interceptor-class fighter.