The USS Thorne was a Federation Starfleet vessel that was active in the 24th century.

In 2332 the Thorne found itself protected from changes in the timeline brought about by time traveling Romulans. In the new timeline, the Federation did not exist as the Andorians gained warp drive earlier and went to war with the Vulcans. With permission from the sole surviving Department of Temporal Investigations member, the crew took the ship back to 1592.

The crew encountered the crew of the Z'rok, a Romulan vessel belonging to the resistance in 1692 of the new timeline; the new 1692 had the Andorians conquer the Alpha and Beta Quadrants. Together, they worked to defeat the original Romulan crew and restore history. At that point, the Thorne returned to a restored 2332. (Last Unicorn RPG module: All Our Yesterdays: The Time Travel Sourcebook)