The United Earth Space Probe Agency (abbreviated UESPA) was a part of the United Earth government which was responsible for space exploration.
UESPA evolved, in part, from the United Earth AeroNav Forces of the early 21st century. (TOS novel: Strangers from the Sky)
In 2067, UESPA launched the Friendship One probe toward the Delta Quadrant, as part of a series of unmanned exploration. (VOY episode: "Friendship One")
By the 2130s the United Earth Starfleet had taken UESPA's place as Earth's leading exploratory agency, but the two would continue to cooperate. (ENT episode: "First Flight")
UESPA personnel also aided in the construction of the Enterprise in 2150. (Star Trek: Enterprise)
After the founding of the Federation, UESPA became one of the five sub-commands of the new Federation Starfleet. UESPA was responsible for the exploratory division of the new Starfleet; the USS Enterprise was part of this division. (ENT - Rise of the Federation novel: A Choice of Futures)
UESPA continued to help control Starfleet vessels into the 2260s. James T. Kirk reported the destruction of the USS Antares to UESPA. (TOS episode: "Charlie X")
Later, Kirk informed John Christopher that UESPA was the USS Enterprise's operating authority. (TOS episode: "Tomorrow is Yesterday")
Wheeler Stinson studied accounts of the first days of UESPA. (DS9 novel: Ascendance)
In one alternate timeline, the IKS Qu' was a UESPA vessel prior to its capture by Klingons. (TNG novel: Q & A)
In another alternate universe, UESPA became a purely military organization after several other powers established the Interstellar Coalition. They operated the UESS Enterprise in the 2260s. (Star Trek: Myriad Universes novel: A Less Perfect Union)
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