I've always loved the The Next Generation and would never even dream of someone else portraying Captain Picard or any of the other characters for that matter and hopefully I won't have to witness any change like this (excluding the OS remake) but you never know, at some point in the future it could be a last ditch attempt to get more fans to know of Star Trek TNG's existance.
LETS ALL HOPE THIS NEVER HAPPENS!
But if this were ever to happen tell me, who do you think would be the actors for:
Jean Luc Picard
Geordi La Forge
Wesley Crusher (must be someone annoying)