The Vodrey Nebula was an interstellar gas cloud located on the Federation-Klingon border, near the Maranga and the Hatarian systems. In 2370, a delayed rendezvous with the USS Kearsarge allowed the Stellar Dynamics department on the USS Enterprise-D to complete a study of the Vodrey Nebula. (TNG episode: "Firstborn")

The nebula was later mentioned by Gorkon in the Vanguard novel Precipice by David Mack.

The nebula was named by Star Trek: The Next Generation screenwriters after fan William F.B. Vodrey, who had written to suggest the use of the name Kearsarge for a Starfleet vessel.