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The Vulcan nerve pinch, also known as a neck pinch, was a Vulcan technique in which an individual applied pressure to the nerves near the base of the neck, often causing almost immediate unconsciousness. While primarily used by Vulcans, it could be used by non-Vulcans too. The victims of a Vulcan neck pinch could suffer headaches afterwards. (TOS novel: Enterprise: The First Adventure; TOS episode: "The Enterprise Incident")
Spock has used the Vulcan nerve pinch in quite a few situations. (TOS episodes: "The Enemy Within", "Wolf in the Fold"; TOS comics: "No Time Like the Past", "The Long Night's Dawn!"; TOS movie, novelization & comic adaptation: Star Trek: The Motion Picture)
Some humans such as Captains Jonathan Archer and Jean-Luc Picard are capable of using the Vulcan nerve pinch, possibly due to their experiences with Vulcan mind melds, Leonard McCoy however was incapable of using it against a starfleet security guard on Earth after Spock transferred his katra into McCoy's mind. (TOS movie & novelization: The Search for Spock; TNG episodes: "Sarek", "Starship Mine")