The Vyyoxi were a race, known to Gary Seven, native to a homeworld located somewhere in the Milky Way Galaxy. The Vyyoxi had deployed ozone-depleting weapons on their planet, and had ultimately devastated their civilization.

In the year 1984, Gary Seven listed this as an example of how Wilson Evergreen's technology could be used to do harm rather than good. (TOS novel: The Rise and Fall of Khan Noonien Singh, Volume 1)

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